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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BARD1
All Species:
18.18
Human Site:
S148
Identified Species:
40
UniProt:
Q99728
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99728
NP_000456.2
777
86648
S148
N
S
I
K
M
W
F
S
P
R
S
K
K
V
R
Chimpanzee
Pan troglodytes
XP_526019
777
86498
S148
N
S
I
K
M
W
F
S
P
R
S
K
K
V
R
Rhesus Macaque
Macaca mulatta
XP_001084740
777
86841
S148
N
S
I
K
M
W
F
S
P
R
S
K
K
V
R
Dog
Lupus familis
XP_852715
923
103188
S293
N
S
I
K
M
W
F
S
P
R
S
K
K
V
R
Cat
Felis silvestris
Mouse
Mus musculus
O70445
765
84236
R142
I
K
M
W
F
S
P
R
S
K
K
V
R
Y
V
Rat
Rattus norvegicus
Q9QZH2
768
84530
S142
N
S
V
K
M
W
F
S
P
R
S
K
K
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519813
231
26178
Chicken
Gallus gallus
NP_001026417
750
82934
L141
P
K
T
N
S
N
D
L
C
Q
D
P
S
S
V
Frog
Xenopus laevis
NP_001082131
772
86896
K142
K
Q
K
K
K
Q
I
K
M
W
F
S
P
R
S
Zebra Danio
Brachydanio rerio
XP_001921099
334
36093
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188296
940
102732
R164
E
T
G
K
A
D
R
R
P
G
K
K
R
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.3
68.3
N.A.
69.5
68.5
N.A.
22.5
51.6
47.3
22.1
N.A.
N.A.
N.A.
N.A.
26.8
Protein Similarity:
100
99.7
97.5
74.4
N.A.
81
80.9
N.A.
26.7
67.9
62.8
31.6
N.A.
N.A.
N.A.
N.A.
41.4
P-Site Identity:
100
100
100
100
N.A.
0
86.6
N.A.
0
0
6.6
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
0
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
10
0
46
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
37
0
0
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
10
19
10
64
10
0
0
10
0
10
19
55
46
0
10
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
46
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
46
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
10
0
55
0
0
10
10
0
0
% P
% Gln:
0
10
0
0
0
10
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
19
0
46
0
0
19
10
46
% R
% Ser:
0
46
0
0
10
10
0
46
10
0
46
10
10
10
10
% S
% Thr:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
10
0
37
19
% V
% Trp:
0
0
0
10
0
46
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _